The CAROT Research Vector Core is a facility that specializes in generating recombinant Adeno-Associated Virus (AAV) vectors for applications in retinal and ophthalmic research. The main objective of the Core is to provide custom-made vectors for basic and translational research. The Core will guide investigators on selection of capsids, regulatory elements and other issues that may impact the results. The core can scale the size of the vector preparation according to the needs of the investigator. All vector lots undergo evaluation to assure purity and high quality. Dr. Shangzhen Zhuo, an internationally recognized leader in AAV vector production, directs the core.