Tissue & Stem Cell Bank

CAROT will assist investigators in characterizing and storing cellular reagents that can then be used to study pathogenic mechanisms for various ophthalmic diseases, genotype-phenotype relationships and as substrates with which to test therapeutic strategies. CAROT will bank cells/ tissues from patients with hereditary retinal diseases with the goal of using them (or making them available to other investigators) to develop tailored treatment strategies. Cell lines that will be generated from patient samples include induced pluripotent stem (iPS) cells. This core will also provide expertise to researchers in iPS cell culture for studies of ophthalmic disease. CAROT will bank specific cells upon request. The tissue bank and iPSC core is directed by Dr. Jeannette Bennicelli, who has more than 3 decades experience in maintaining and studying unique cell lines.